Week 3 in the NFL will undoubtedly feature some major twists between the start of Sunday and the end of the "Monday Night Football" doubleheader.

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Miami head coach Mike McDaniel is just 5-8 against the spread as an underdog and is facing a Seahawks defense that ranks third in pass rush win rate and fifth in DVOA. The Dolphins do have the advantage of extra rest, but the Seahawks are getting solid play from Geno Smith and rank second in expected points contributed by passing defense.

The biggest favorite in the NFL has blown up survivor pools for a 2nd straight week, as the Baltimore Ravens (0-2) lost 26-23 to the visiting Las Vegas Raiders (1-1) in Week 2 -- Baltimore was favored by 8.

The Steelers and Chargers were coin flips to make the NFL playoffs at the beginning of the 2024 season according to the NFL odds. However, after both teams started the season 2-0, their chances are looking up and they'll go head-to-head in a critical AFC matchup on the Week 3 NFL schedule.

Several teams are seeking redemption after puzzling starts this NFL season. Get our previews, predictions and picks for every game.

Before looking at SportsbookWire staff's Week 3 NFL picks, here are the against-the-spread (ATS) and Over/Under (O/U) leaders, according to Teamrankings.com. Six teams are 2-0 ATS. They are the Arizona Cardinals (1-1 straight-up record),

NFL Week 3 picks, predictions for every game, including Patriots-Jets, Eagles-Saints, Dolphins-Seahawks, Ravens-Cowboys, 49ers-Rams, Chiefs-Falcons.

Getting the best Week 3 NFL score predictions can help you make the best NFL against the spread picks, NFL money line picks, and NFL over-under picks on those matchups and others. Before you make any Week 3 NFL picks,